"What you talkin' 'bout, Willis?" - Arnold Jackson
Young Gary Coleman was perfect during his time on Diff’rent Strokes. His character, pint-sized Arnold Jackson, was a larger than life personality, always with something slick to say. However, his most famous quip was the classic line "What you talkin' 'bout, Willis?", complete with a screwed-face and raised eyebrow. You can go on YouTube right now to see how many kids and adults alike have tried to reinterpret the line in the same fashion as Coleman. None have been able to compare, though.