4. 50 Cent vs. The Game
Known for impacting the careers of his foes, one of the few that survived a rap beef with 50 Cent was his former protégé The Game. Cosigned by the visionary Dr. Dre, The Game was welcomed into 50’s G-Unit crew, with their fruitful relationship resulting in singles “How We Do” and “Hate It or Love It” from his smash debut The Documentary. In a turn of events that is almost to be expected given the parties involved, things soured with The Game releasing “300 Bars,” a nearly 15-minute barrage of anger against his former benefactors. Given their chemistry, fans are still left wondering what they could have achieved together under more friendly circumstances.